KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEATR1
All Species:
30
Human Site:
T1300
Identified Species:
50.77
UniProt:
Q9H583
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H583
NP_060542.4
2144
242370
T1300
R
L
S
E
M
P
Q
T
H
H
H
A
L
L
L
Chimpanzee
Pan troglodytes
XP_001156974
2144
242420
T1300
R
L
S
E
M
P
Q
T
H
H
H
A
L
L
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536334
2141
242568
T1300
R
V
S
E
M
P
Q
T
H
H
H
A
L
L
L
Cat
Felis silvestris
Mouse
Mus musculus
NP_659084
2143
242053
T1300
R
L
S
E
M
P
Q
T
H
H
H
A
L
L
L
Rat
Rattus norvegicus
NP_001101888
2143
241191
T1300
R
L
S
E
M
P
Q
T
H
H
H
A
L
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422958
2155
244590
T1311
R
I
S
K
M
P
Q
T
H
H
H
A
L
L
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SY48
2159
242032
T1295
R
V
S
E
M
P
Q
T
H
H
H
A
L
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VM75
2096
237201
T1260
R
N
T
R
N
P
Q
T
Q
Q
H
A
L
L
F
Honey Bee
Apis mellifera
XP_393800
2028
231830
R1201
T
I
K
K
L
P
I
R
D
A
H
L
Q
I
D
Nematode Worm
Caenorhab. elegans
Q23495
1650
185210
N876
I
E
L
L
S
A
L
N
P
F
E
Q
L
S
S
Sea Urchin
Strong. purpuratus
XP_794611
1635
181917
H861
T
R
G
S
S
E
C
H
L
K
D
K
T
R
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C8Z4
2001
224001
L1203
I
A
S
L
L
D
M
L
L
L
K
K
D
L
T
Baker's Yeast
Sacchar. cerevisiae
P42945
1769
200063
I995
L
T
V
V
P
A
L
I
K
N
S
K
G
N
E
Red Bread Mold
Neurospora crassa
Q7RZM8
1788
196873
R1014
L
L
V
A
S
L
A
R
T
A
P
D
V
V
L
Conservation
Percent
Protein Identity:
100
99.5
N.A.
89.7
N.A.
83.8
84.9
N.A.
N.A.
65.5
N.A.
54.5
N.A.
28.6
30.5
21.1
24.4
Protein Similarity:
100
99.8
N.A.
95
N.A.
92.1
92.7
N.A.
N.A.
80.5
N.A.
73
N.A.
49.4
50.8
38.9
43.2
P-Site Identity:
100
100
N.A.
93.3
N.A.
100
100
N.A.
N.A.
86.6
N.A.
93.3
N.A.
53.3
13.3
6.6
0
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
100
N.A.
100
N.A.
60
40
6.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.4
21.2
23
Protein Similarity:
N.A.
N.A.
N.A.
43.4
40.2
42.2
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
20
6.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
0
15
8
0
0
15
0
58
0
0
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
8
0
8
8
8
0
8
% D
% Glu:
0
8
0
43
0
8
0
0
0
0
8
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
8
50
50
65
0
0
0
0
% H
% Ile:
15
15
0
0
0
0
8
8
0
0
0
0
0
8
0
% I
% Lys:
0
0
8
15
0
0
0
0
8
8
8
22
0
0
0
% K
% Leu:
15
36
8
15
15
8
15
8
15
8
0
8
65
65
58
% L
% Met:
0
0
0
0
50
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
8
0
0
8
0
8
0
0
0
8
0
% N
% Pro:
0
0
0
0
8
65
0
0
8
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
58
0
8
8
0
8
8
0
8
% Q
% Arg:
58
8
0
8
0
0
0
15
0
0
0
0
0
8
0
% R
% Ser:
0
0
58
8
22
0
0
0
0
0
8
0
0
8
8
% S
% Thr:
15
8
8
0
0
0
0
58
8
0
0
0
8
0
8
% T
% Val:
0
15
15
8
0
0
0
0
0
0
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _